‘Gentle’ quickly growing hospitalizations and different tidbits
UK chief medical officers: “Knowledge on severity will change into clearer over the approaching weeks however hospitalisations from Omicron are already occurring and these are prone to improve quickly”
Omicron escapes the antibodies generated by the vaccine, to a terrific diploma. Whole mAB remedies have been rendered ineffective.
B.1.1.529 (Omicron) escapes nearly all of SARS-CoV-2 neutralizing antibodies of various epitopes
https://www.biorxiv.org/content material/10.1101/2021.12.07.470392v1
This has been verified by prime German labs. (Translate)
The monoclonal AKs imdevimab and casirivimab are – as anticipated – ineffective with Omicron
https://twitter.com/CiesekSandra/status/1468465347519041539?s=20
https://twitter.com/CiesekSandra/status/1468465720606527489?s=20
We are able to see Omicron’s discount in binding functionality within the visualization under from Bloom Lab
Right here’s whole calculated RBD antibody binding to Omicron (w/o R346K) & #SARSCoV2 variants. Omicron has a lot much less binding than different variants; is near synthetic spike polymutant PMS20
https://twitter.com/jbloom_lab/status/1468001925496860677?s=20
